CURRENT IN NEONATOLOGY LITERATURE TEST
CURRENT IN NEONATOLOGY LITERATURE CERTIFICATION TEST (Vol 1, Is 2)
Instructions:
1. copy the entire test below into a new open email (as if you are about to compose and send).
2. Address email to eneoresearch@gmail.com
3. Fill out the answers to the questions, by deleting all of the wrong answers and leaving the only possible correct answer.
4. Be sure to put your name on the bottom of the test (so that we can add it to the certificate we send you).
5. Send the email (with the completed test inside of it) to us. We will grade it and if you pass, we will send you a certificate of completion.
CURRENT IN NEONATOLOGY LITERATURE CERTIFICATION TEST (Vol 1, Is 2)
Good for 2 points of non-CME credit, (anticipated time to complete is 2 hours)
1] Which of the following statements best describes the current thinking regarding the importance of NFkB in the genesis of chronic lung disease
a. NFkB activation increases in response to both the oxidative and inflammatory injury that is associated with chronic lung disease, potentially making it either a mediator or biomarker that researchers are hoping to utilize for therapeutic intervention in the future
b. NFkB activation decreases in response to both the oxidative and inflammatory injury that is associated with chronic lung disease, potentially making it either a mediator or biomarker that researchers are hoping to utilize for therapeutic intervention in the future
c. NFkB activation does not change in response to either the oxidative or inflammatory injury that is associated with chronic lung disease, making it a poor candidate for therapeutic intervention in the future
2] Which of the following statements does not describe a true difference between those states with certificate of need (CON) legislation (and CON-regulation of their NICUs) versus those without?
a. There is a higher overall infant mortality rate in states without effective CON-based regulation.
b. There are more level III units in states without CON.
c. There are more very low birth weight infant deaths in states without CON-based regulation.
d. States with CON-based regulation, had more beds per level III NICU in the metropolitan facilities.
3] Which of the following statements is not true regarding Omegaven?
a. It reverses cholestasis when compared to soybean based lipid emulsions (and does so faster).
b. It reduces the need for liver transplant in short bowel patients.
c. It has been approved by the FDA.
d. It is sufficient for IV lipid nutrition as a mononutrient.
4] In a follow up of the Caffeine for Apnea Study, which of the following findings was found to be the opposite of previous findings in the literature?
a. Infants who received caffeine earlier had worse neurodevelopmental outcomes.
b. Infants who required longer periods of mechanical ventilation had fewer episodes of apnea.
c. Infants who received greater levels of intense resuscitation at birth had no difference in neurodevelopmental outcomes when compared to less intensely resuscitated infants.
d. Infants who did not receive caffeine were more likely to lose weight in the first two weeks of life.
5] With regard to fulminant, fatal NEC, which of the following associated variables seem least likely to be related to clinical practice parameters that could be altered?
a. rapid escalation of feeds in the days immediately prior to onset.
b. Increase in human milk fortifier 48 hours prior to onset.
c. high I/T ratio.
d. Anemia < 22%.
6] With regard to infants who die from NEC in general, which of the following statements is not true?
a. 2/3rds of infants who die from NEC die within the first 7 days.
b. Infants who die from NEC in the first 7 days are spread across the gestational age spectrum relatively equally compared to those who die later (who are more premature).
c. Infants who die from NEC are more likely to be African American.
d. Infants who die from NEC in the first 7 days are less likely to have been on a high frequency ventilator at the time of diagnosis.
7] With regard to planned home births in the state of Missouri, which of the following is actually true?
a. An infant born to a planned home birth is much more likely to suffer a neonatal seizure or death than an infant born in a birthing center or hospital.
b. An infant born to a planned home birth is less likely to suffer a neonatal seizure or death than an infant born in a birthing center or hospital.
c. An infant born to a planned home birth is much more likely to suffer a neonatal seizure but less likely to suffer a death than an infant born in a birthing center or hospital.
e. An infant born to a planned home birth is less likely to suffer a neonatal seizure but more likely to suffer a death than an infant born in a birthing center or hospital.
8] Regarding the ELGANS study using 25 bloodspot proteins to determine associations with chronic lung disease, which of the following is the most appropriate conclusion for this study?
a. elevated concentrations of VEGF and RANTES are associated with abnormal lung development, whereas elevated concentrations of IL-18 and ICAM-1 were associated with normal lung development.
b. elevated concentrations of VEGF and RANTES are associated with normal lung development, whereas elevated concentrations of IL-18 and ICAM-1 were associated with abnormal lung development.
c. depressed concentrations of VEGF and RANTES are associated with abnormal lung development, whereas depressed concentrations of IL-18 and ICAM-1 were associated with abnormal lung development.
d. depressed concentrations of VEGF and RANTES are associated with normal lung development, whereas depressed concentrations of IL-18 and ICAM-1 were associated with normal lung development.
9] With regard to the NICHD retrospective analysis on the effects of early nutrition upon the influence of severity of illness, in VLBW infants, which of the following statements are not true?
a. infants who are more ill tend to get less nutrition but more total fluid.
b. Infants who were more severely ill could not have their composite scores of NDI and death substantially adjusted by improved nutrition.
c. Infants who were SGA and severely ill demonstrated improved NDI and death outcomes with early nutritional adjustment, similar to that of AGA infants.
10] With regard to the NICHD’s retrospective analysis of phototherapy use and neurodevelopmental outcomes in infants < 1000 grams, which of the following answers is clearly wrong?
a. previous studies have found lower Bayley scores in infants born 500-1000 grams who received phototherapy versus those who did not.
b. this study found more low Bayley scores in infants born 500-1000 grams who received phototherapy versus those who did not, but was not sufficiently powered to be conclusive.
c. there is concern that phototherapy might increase systemic oxidative injury in infants 500-1000 grams birth weight because of their thin skin (as a light barrier) and limited ability to scavenge oxygen free radicals.
d. this retrospective study demonstrates that the use of phototherapy in infants born 500-1000 grams is more risky than the risk of kernicterus in those with rising bilirubins
11] what is your name? _______________________________
12] what institution did you complete your neonatal fellowship at? ___________________
13] what year did you complete your neonatal fellowship?
14] What is you medical license number? _____________________________
