The e-Journal of Neonatology Research

Your open access, online source for everything in neonatology

Volume 2, Issue 4, Fall 2012 (Special NEC edition)

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Welcome to our Special edition on NEC: There’s Still a Lot to Learn

Jonathan Swanson


What do Neos think about the feasibility of approaching NEC like we do central line infections (i.e. zero tolerance)?


1. Mapping the New World of Necrotizing Enterocolitis (NEC): Review and Opinion

Phillip Gordon, Robert Christensen, Jörn-Hendrik Weitkamp and Akhil Maheshwari


2. Matched Comparison Study of Whole Body Cooling Therapy With and Without a Single Dose of Aminophylline for Improved Renal Function

Euming Chong, Brooke Vergales, Jane Reynolds, Shelley Thibeau, Victor Lunyong, Santina Zanelli, Karen Fairchild, and Phillip Gordon


3. Detailed Analysis of NEC Risks Across a Decade in a Low Incidence NICU: Can We Drive the Incidence of NEC Toward Zero?

Joshua Benjamin, Euming Chong, Jane Reynolds, and Phillip Gordon


4. Mortality Trends and Cause of Death among Infants Weighing 2.5 kg or more at Birth in an Inner City Hospital over an 18 year Period

Zehra Panjvani, Edgar Torres, Rhina Castillo, and B. K. Rajegowda



The Incidence of NEC is Twice as High in Infants with Gastroschisis

Phillip Gordon, Diane Lambert and Robert Christensen


Extraordinary Service in the Face of Super Storm Sandy

The Editors of the e-Journal of Neonatology Research


1. Sabir H, Jary S, Tooley J, Liu X, Thoresen M. Increased Inspired Oxygen in the First Hours of Life is Associated with Adverse Outcome in Newborns Treated for Perinatal Asphyxia with Therapeutic Hypothermia. J Pediatr. 2012 Sep;161(3):409-16. Epub 2012 Apr 18.

2. Aikio O, Metsola J, Vuolteenaho R, Perhomaa M, Hallman M. Transient defect in nitric oxide generation after rupture of fetal membranes and responsiveness to inhaled nitric oxide in very preterm infants with hypoxic respiratory failure. J Pediatr. 2012 Sep;161(3):397-403.e1. Epub 2012 May 1.

3. Wickremasinghe AC, Rogers EE, Piecuch RE, Johnson BC, Golden S, Moon-Grady AJ, Clyman RI. Neurodevelopmental Outcomes Following Two Different Treatment Approaches (Early Ligation and Selective Ligation) for Patent Ductus Arteriosus. J Pediatr. 2012 Jul 12. [Epub ahead of print]

4. Mirea L, Sankaran K, Seshia M, Ohlsson A, Allen AC, Aziz K, Lee SK, Shah PS; Canadian Neonatal Network. Treatment of patent ductus arteriosus and neonatal mortality/morbidities: adjustment for treatment selection bias. J Pediatr. 2012 Oct;161(4):689-694.e1.

5. Patel J, Posencheg M, Ades A. Proficiency and retention of neonatal resuscitation skills by pediatric residents. Pediatrics. 2012 Sep;130(3):515-21.

6. Fergusson DA, Hébert P, Hogan DL, LeBel L, Rouvinez-Bouali N, Smyth JA, Sankaran K, Tinmouth A, Blajchman MA, Kovacs L, Lachance C, Lee S, Walker CR, Hutton B, Ducharme R, Balchin K, Ramsay T, Ford JC, Kakadekar A, Ramesh K, Shapiro S. Effect of fresh red blood cell transfusions on clinical outcomes in premature, very low-birth-weight infants: the ARIPI randomized trial. JAMA. 2012 Oct 10;308(14):1443-51.

7. Zimmerman E, Lahav A. Ototoxicity in preterm infants: effects of genetics, aminoglycosides, and loud environmental noise.J Perinatol. 2012 Aug 9. [Epub ahead of print]

8. Al-Wassia H, Alshaikh B, Sauve R. Prophylactic theophylline for the prevention of severe renal dysfunction in term and post-term neonates with perinatal asphyxia: a systematic review and meta-analysis of randomized controlled trials. J Perinatol. 2012 Jul 26. [Epub ahead of print]

9. Cheldelin LV, Dunham S, Stewart V. NICU patient satisfaction: how you measure counts. J Perinatol. 2012 Sep 13. [Epub ahead of print]

10. Watson A, Saville B, Lu Z, Walsh W. It is not the ride: inter-hospital transport is not an independent risk factor for intraventricular hemorrhage among very low birth weight infants. J Perinatol. 2012 Oct 4. [Epub ahead of print]



Five excellent contemporary reviews on acquired neonatal gut disease:

1. Mapping the New World of Necrotizing Enterocolitis (NEC): Review and Opinion, Gordon PV, Christensen R, Weitkamp JH, Maheshwari A. e-J Neonatol Res, 2012; 2(4):145-72.

2. Necrotizing enterocolitis risk: state of the science. Gephart SM, McGrath JM, Effken JA, Halpern MD. Adv Neonatal Care. 2012 Apr;12(2):77-87. Review.

3. New insights into the pathogenesis and treatment of necrotizing enterocolitis: Toll-like receptors and beyond. Afrazi A, Sodhi CP, Richardson W, Neal M, Good M, Siggers R, Hackam DJ. Pediatr Res. 2011 Mar;69(3):183-8. Review.

4. Necrotizing enterocolitis. Neu J, Walker WA. N Engl J Med. 2011 Jan 20;364(3):255-64. Review.

5. Understanding intestinal vulnerability to perforation in the extremely low birth weight infant. Gordon PV. Pediatr Res. 2009 Feb;65(2):138-44. Review


Video Link

  Dr David Hackam

  New Research in Necrotizing Enterocolitis – Artificial Intestine a Therapy for NEC?



FDA extends Simply Thick Warning to include risk of life threating bowel disease in all ages (term and preterm)

Grab Bag

The Institute of Medicine’s Summary Report from the Workshop on The Human Microbiome, Diet and Health

ACGME program guidelines for Neonatal Perintal Fellowship Programs – Please note, neonatal fellows will no longer be required to be directly involved in the care of surgical NICU patients in 2013.

The ACGME’s “Next Accreditation System” and the Council for Pediatric Subspecialty’s current response

Carreer Paths in Neonatology by Marlynn Escabado and John Hartline – via the American Academy of Pediatrics


Contemporary Forums The Fetus and Newborn:  State of the Art Care  San Francisco, CA October 28-31, 21021

Contemporary Forums Developmental Interventions in Neonatal Care November 7-10, 2012  Orlando, FL

Hot Topics in Neonatology  December 2-4, 2012 Washington, DC

Contemporary Forums:  Developmental Interventions in Neonatal Care November 7-9, 2012 Orlando, FL

NEO:  The Conference for Neonatology   February 19-24, 2013 Orlando, FL

35th Annual Current Concepts in Neonatal and Pediatric Transport Conference February 25-27, 2013 Salt Lake City, UT



There was one rejected manuscript(s) and zero rejected letter(s) for this volume (we will NOT publish specific information about individual rejections).

Written by Dr Phillip Gordon

November 5th, 2012 at 10:41 pm

Posted in Uncategorized

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